Primary Sclerosing Cholangitis
PSC is a chronic liver disease caused by inflammation and scarring of the bile ducts in the liver. The inflammation restricts the flow of bile into the gut, which can lead to very severe problems such as cirrhosis of the liver, liver cancer, and liver failure. The cause is said to be autoimmunity and the best case for treatment and recovery is full liver transplantation. Symptoms associated are chronic fatigue, sever jaundice, profound itching, malabsorption of fats, pale stools, and dark urine. A diagnosis can typically be made through imaging of the bile duct via an ERCP.
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